Repetitive transcranial magnetic stimulation (rTMS) has been used in the treatment of primary insomnia (PI). Since PI is a functional disorder with abnormal brain network connections, our network-based TMS offers a valuable method for directly affecting dynamic connectivity of different brain regions.
In a recent study1, it is reported that various ratings of patients with PI decreased significantly after rTMS treatment. TMS treatment improved significantly better stage III sleep and REM sleep cycle compared with control groups, as well as indices of hypothalamic-pituitary-adrenal (HPA) and hypothalamic–pituitary–thyroid (HPT) axes.
We offer low-frequency rTMS targeting regions determined by fMRI imaging within the right dorsolateral prefrontal cortex or the posterior parietal cortex, which are known to have significant positive effects on the treatment of PIs1,2.
1. Jiang CG, Zhang T, Yue FG, Yi ML, Gao D. Efficacy of repetitive transcranial magnetic stimulation in the treatment of patients with chronic primary insomnia. Cell Biochem Biophys. 2013 Sep;67(1):169-73.
2. Nardone R, Sebastianelli L, Versace V, Brigo F, Golaszewski S, Pucks-Faes E, Saltuari L, Trinka E. Effects of repetitive transcranial magnetic stimulation in subjects with sleep disorders. Sleep Med. 2020 Jul;71:113-121.