TMS Therapy for Eating Disorders

fMRI TMS Can Identify and Correct the Network Causing an Eating Disorder

There is a commonly-held misconception that eating disorders are a lifestyle choice. Eating disorders (EDs) are serious and are associated with severe disturbances in people’s eating behavior, related thoughts, and emotions.

Preoccupation with food, body weight, and shape may also signal an eating disorder. Common eating disorders include anorexia nervosa (AN), bulimia nervosa (BM), and binge-eating disorder. In the study of brain circuitry underlying EDs, scientists have focused on the reward circuitry. Eating palatable food increases activation in regions involved in reward such as the ventral and dorsal striatum, midbrain, amygdala, and orbitofrontal cortex1

Decreased fronto-caudate connectivity in a patient with anorexia nervosa
Decreased fronto-caudate connectivity in a patient with anorexia nervosa (cortical-subcortical view)
Decreased fronto-caudate connectivity in a patient with anorexia nervosa (subcortico-cortical view)
Decreased fronto-caudate connectivity in a patient with anorexia nervosa (subcortico-cortical view)

Increased or decreased functional resting-state connectivity has also been observed in EDs compared to controls, implicating networks associated with executive function, reward processing, and perception2. Choosing low-fat vs. high-fat foods increases connectivity between dorsal caudate and dorsolateral prefrontal (DLPFC) regions in patients with AN, which is implicated in actual food intake eaten, thus making the DLPFC a region of considerable interest3.

There is evidence for EDs symptom reduction following rTMS in both AN and BN4-6. As such, TMS has potential for reducing EDs symptomatology and related behaviours, and for altering food intake and body weight.

By identifying the underlying network associated with the disorder through fMRI imaging, we can treat the biological side of this disorder. Call us to understand more about our unique approach.

References

View sources here: https://neurotherapeutixnyc.com/sources/

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Meet Neurotherapeutix NYC

Neurotherapeutix is the leading clinic for functional imaging guided transcranial magnetic stimulation (TMS), a safe, innovative, and non-invasive methodology for treating a wide range of acute and chronic mental disorders and brain injuries. Our advanced fMRI technology allows us to map the brain for the… Learn More »

By: Neurotherapeutix NYC

Reviewed By: Marta Moreno, Ph.D

Published: March 24, 2023

Last Reviewed: September 27, 2024

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